Skin penetration & bioavailability :

An active that does not reach its target does nothing, whatever the in vitro efficacy data says. Penetration work is the least glamorous and most decisive testing we do, and it settles arguments that nothing else can.

WHAT WE RUN

•  In vitro skin absorption using Franz diffusion cells — OECD 428

•  Percutaneous penetration kinetics

•  Active release and in vitro release testing (IVRT)

•  Comparative bioavailability between formulations

WHAT YOU RECEIVE

Mass balance, penetration profile over time, distribution between the skin compartments, and a direct comparison where more than one formulation is under study.

WHO THIS IS FOR

Formulators choosing between delivery systems, ingredient developers demonstrating that an active is bioavailable, and anyone whose claim depends on the word "penetrates".

CALL TO ACTION

Discuss a skin penetration & bioavailability project